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KMID : 0359719950130020305
Journal of the Korean Neurological Association
1995 Volume.13 No. 2 p.305 ~ p.310
Polymorphonuclear CSF Pleocytosis During the Treatment of Tuberculous Meningitis




Abstract
among 73 patients with possible and definite tuberculous meningitis, 14 cases showed a sudden unexpectied polymorhonuclear(PMN) CSF pleocytosis during treatment. Patients with superimposed bacterial meningitis were excluded. Eleven
patients(15.1%)
matched inclusion criteria. The intervals between the onset of the treatment and the onset of the PMN CSF pleoctosis were 7-54 dyas9mean 17.2¡¾14.4 dys). The mean duration of PMN CSF pleocytosis was 14.2¡¾12.4 days A PMN CSF pleocytosis may
develop
occasionally weeks or months after the start of the treatment for tuberculous meningitis. Though the cause is uncertiain, we suggest that probly its cause is superimposed acute meningeal inflammation by the release of Mycobacterium from
tuberculomas or
delayed Jarisch-Herxheimer reaction.
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